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Test Code MET Methemoglobin and Sulfhemoglobin, Blood

Reporting Name

Methemoglobin and Sulfhemoglobin, B

Useful For

Diagnosing methemoglobinemia and sulfhemoglobinemia

 

Identifying cyanosis due to other causes, such as congenital heart disease

Profile Information

Test ID Reporting Name Available Separately Always Performed
METH Methemoglobin, B No Yes
SULF Sulfhemoglobin, B No Yes

Method Name

Spectrophotometry (SP)

Performing Laboratory

Mayo Medical Laboratories in Rochester

Specimen Type

Whole Blood EDTA

Specimen Required

Specimen must arrive within 72 hours of draw.

 

Container/Tube: Lavender top (EDTA)  

Specimen Volume: Full tube

Additional Information: Patient's age is required.

Forms: If not ordering electronically, please submit a Hematopathology/Molecular Oncology Request Form (Supply T241) with the specimen.

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time
Whole Blood EDTA Refrigerated 72 hours

Reference Values

METHEMOGLOBIN

0-11 months: not established

≥1 year: 0.0-1.5% of total hemoglobin

 

SULFHEMOGLOBIN

0-11 months: not established

≥1 year: 0.0-0.4% of total hemoglobin

Day(s) and Time(s) Performed

Monday through Saturday; Continuously

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

83050-Methemoglobin

83060-Sulfhemoglobin

LOINC Code Information

Result ID Reporting Name LOINC Code
8268 Methemoglobin, B 2614-6
8272 Sulfhemoglobin, B 4685-4

Cautions

Methemoglobin is unstable and is reduced to hemoglobin at a rate of about 40% per day at 0 to 4° C.

 

A normal methemoglobin value obtained with stored or shipped specimens does not exclude prior mild methemoglobinemia. However, significant methemoglobinemia will still be demonstrable.

 

Sulfhemoglobin is stable and does not change in stored or shipped specimens.

Analytic Time

Same day/1 day

Specimen Retention Time

7 days

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

NA

Icterus

NA

Other

NA